I believe the biggest problem of working remotely is not solvable by technology. Yes you can share you screens in multiple ways, communicate using im, voice, email etc. but you still dont have real human interactions. You sit alone at home behind your machine (probably in underwear) only connected to the world through a wire. This can be dangerous in the long term so my advice is to get into a co-working space or get your human interactions elsewhere. For example by switching the places from where you work from time to time or use your breaks for a bit more social activities (workouts!).

This oatmeal comic summed up the good and bad pretty good imo http://theoatmeal.com/comics/working_home