It matters more for financial contributions and other support than for the vote. Writing off California makes sense for libertarians, but I could imagine single-issue Bay Area tech voters who are newly rich and techie and might aggressively support a candidate over this.
I personally think the President's power is limited enough, and have enough faith in the judiciary (and overall faith in the bureaucrats who make up the government) that I'd go single-issue on any of a few issues. If there were a Republican or Democrat who wanted to "fix" firearms, IP, debt, entitlements, end foreign occupations and the drug war, and/or fix the tax code, I'd consider working for him for a campaign, donating the max to superpacs, etc., if I thought he could win. I'd be ok if that candidate was against gay rights (since the courts would protect the gains so far, and could extend them), was short or ugly, etc.
I personally think the President's power is limited enough, and have enough faith in the judiciary (and overall faith in the bureaucrats who make up the government) that I'd go single-issue on any of a few issues. If there were a Republican or Democrat who wanted to "fix" firearms, IP, debt, entitlements, end foreign occupations and the drug war, and/or fix the tax code, I'd consider working for him for a campaign, donating the max to superpacs, etc., if I thought he could win. I'd be ok if that candidate was against gay rights (since the courts would protect the gains so far, and could extend them), was short or ugly, etc.