Yes, but even with my worst handwriting, in situations where I and l matters, I can always choose to do an especially I I or particularly l l even if most are indistinguishable which a font can not do
I can see how you'd do an especially I I. You just need to include the serifs, which I always do in handwriting anyway.
But how do you emphasize a lowercase 'l'? The only method I know is to make it cursive, which looks terrible.
(I don't really need to distinguish l from I, because I put serifs on I. But I do sometimes need to distinguish it from 1; in natural writing, 1 and l are identical.)