The problem is nature throws far more in the way of hazardous stuff at us than what we add. And there's basically zero acknowledgement of it, let alone any attempt to regulate it.

And the basic reason to think glyphosphates are safe is the attack mechanism doesn't apply to our metabolism and environmental persistence was believed to be very short. (Turns out there are edge cases in the latter.) And it still comes down to how does it compare to the natural risk?