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reprogramming, is not resetting. the "reprogramming" happens constantly, as a consequence of feedback driven regulation, not as a consequence of meiosis.

there is a phase of error correction that occurs after chromosomal replication, and segregation, to mitigate the damage that is part of meiosis.

if you reset; reprogram, epigenetic regulatory features during meiosis the most frequent outcome is lethal allelic dose or oncogenesis [cancer] why?

embryogenic genes, responsible for early development, are deactivated. expression of these genes are the processes of cancer, unregulated growth, and multiplication, aberrant cell signalling, loss of adhesion to surroundfing tissue structure, aberrant migration [metastasis].

the "reprogramming" [regulation of expression] is facultative, and partial, not total, and obligate.

this is why epigenetic phenomenon exist, else it would be wiped out prior to embryogenesis, and there would be no context specific expression.



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