> Vitamin D, Omega 3, and possibly Magnesium and Creatine.
Vitamin D supplementation is mildly helpful for those with low baseline levels. However the benefits have been exaggerated across the internet and podcasts. A lot of studies show no measured reduction in things like frequency of respiratory infections ( https://pubmed.ncbi.nlm.nih.gov/38178229/ for example, which funnily enough had the Vitamin D3 treated men getting more respiratory infections).
Omega 3 has also been greatly exaggerated. Later large scale studies have shown minimal to no effects.
Magnesium is another one that can be helpful for those who are deficient, but due to the long duration within the body a lot of the supplement fanatics who consume large doses of magnesium might be getting too much over time. Gwern did some self-experimentation where magnesium might have possibly been net negative over time: https://gwern.net/nootropic/magnesium
Creatine is the latest trend. If you believe the latest trends you need to consume a huge amount daily and it will fight off everything from depression to low energy. This is another one where the most impressive studies are all very small, but the larger the study the less impressive the results. The influencers only talk about the small, impressive studies, of course.
It turns out that the vast majority of the USA POPULATION, which I think we have some of the best data for, is magnesium deficient or 50%. The issue is basically vitamins are a catalyst, and is very difficult to justify putting more catalyst into any type of chemical equation. So overdosing on magnesium doesn't make a lot of sense to me.
But I didn’t get my information from “the Internet and podcasts”. I read the actual replicated peer-reviewed studies. Granted, the benefits are not overwhelming.
Vitamin D supplementation is mildly helpful for those with low baseline levels. However the benefits have been exaggerated across the internet and podcasts. A lot of studies show no measured reduction in things like frequency of respiratory infections ( https://pubmed.ncbi.nlm.nih.gov/38178229/ for example, which funnily enough had the Vitamin D3 treated men getting more respiratory infections).
Omega 3 has also been greatly exaggerated. Later large scale studies have shown minimal to no effects.
Magnesium is another one that can be helpful for those who are deficient, but due to the long duration within the body a lot of the supplement fanatics who consume large doses of magnesium might be getting too much over time. Gwern did some self-experimentation where magnesium might have possibly been net negative over time: https://gwern.net/nootropic/magnesium
Creatine is the latest trend. If you believe the latest trends you need to consume a huge amount daily and it will fight off everything from depression to low energy. This is another one where the most impressive studies are all very small, but the larger the study the less impressive the results. The influencers only talk about the small, impressive studies, of course.