My recollection is that Adobe was slow to migrate from 32-bit to 64-bit x86 because they were still dependent on many of the Carbon APIs (Mac OS 9 compatibility) and those APIs weren't carried over to 64-bit. They dragged their heels about transitioning to Cocoa (NeXT derived) APIs for their UI, and it showed.
It still kills me that Altsys/Aldus/Macromedia let their NeXT codebase for Altsys Virtuoso whither (v2 was essentially Freehand 4 w/ a couple of unfixed bugs) so that when Rhapsody was announced they weren't ready for it.
In some other timeline, I am using a Mac w/ a current version of Macromedia Freehand running on Rhapsody and I am a _much_ happier person.
As it is, I'm about to give up on interactive vector drawing and just code everything either using METAPOST or OpenSCAD, or some mix of both.