no, they just mentioned it because they're aware of that but cannot control it and might affect the end result. makes sense - it used to be underdiagnosed and now with bigger push for prevention this might introduce more false positives.
Or even short-term for that matter: even for localized pancreatic adenocarcinoma (not metastasized to lymph nodes or beyond) only 50% of patients survive their first year. For glioblastoma it is even worse: only 25% one-year survival rate
CART therapies and mRNA vaccines are having breakthrough level results in recent studies.
It’s an amazing time in that space. My poor late wife succumbed to metastatic melanoma last year. In 2010, the chances of living a year was 0. Now 5 year survival rates are 65% thanks to immunotherapy. Unfortunately, complications delayed treatment for my wife and she was one of the 35%.
In the next decade, many brain cancers will be curable. Unfortunately, those breakthroughs are built on the shoulders of those who come before us.