If she doesn't get it, she's either selfish or you didn't managed to get her to a point where she supports you blindly so you're screwed anyway. So yes, file a divorce for at least one's sake.
My wife spent twenty years as a Hospice social worker.
Some of the homes she went into had a panoramic view of open water. Some were house trailers with an addition consisting of a hole in the wall, a van without rear doors, duct tape and a tarp. Some were worse.
At times it involved getting up in the middle of the night and watching someone die. At times she knocked on the door and found the body. Once it had been feeding the cats. The time she found the lady who had fallen between the toilet and wall and survived four days despite being stuck was probably worse.
She had clients who were suffering the slow debilitation of Alzheimer's, clients who were losing body parts, and clients who were facing death in the prime of their life.
All the while, she had those clients' families. Some were close, some weren't. She told me that death doesn't fix dysfunction.
If we had a dollar for every time I didn't get it, or was selfish, I'd be an angel investor.
As a married guy with a startup, I am not sure I agree with this.
It took my wife a long time to understand what the life of a founder is like and getting here there was equal parts work for both of us. I spent a lot of time and energy in pervious startups making sure she could see what was going on and why it was important. I also made sure she understood why the whole thing is important to me on a personal/life level.
I don't think it's fair to say "she's selfish". She/he is probably more scared, a little jealous, and feeling un-engaged.
There is no decent scenario for a founder where his/her partner supports them "blindly". If you come to know these people, "the other half", you'll probably see that it is the opposite of blind. They see and know everything that is going on and they work their ass off to make sure their husband/wife is still human through it all.
In that last case, get a divorce?