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"L-Glucose was also found to be a laxative," perhaps another factor in it's adoption.


So wait, is this another Olestra? Guess it depends on what kind of response you get in the gut.


Actually that likely means there is a microbiome component, unfortunately


Or just an osmotic effect.


In what quantities? Often these tests use implausibly large amounts.


It is the same/similar mechanism as the infamous sugar free gummy bears.

https://www.healthline.com/health/food-nutrition/sugar-free-...


If you are looking for high speed mass discharge a heaping teaspoon of xylitol or maltitol (what is in sugar free gummy bears) plus coffee will do the trick within 15 minutes.


Be warned that you risk serious dehydration and/or electrolyte imbalance if you try this.

What's used medically for this purpose (e.g. before a colonoscopy) is an osmotically balanced solution of polyethylene glycol, typically referred to as Macrogol.

Takes a couple of hours of continuous sipping, close to 1 liter total for an adult to get everything flushed, then you'll be discharging almost clear fluid by the end.


> Be warned that you risk serious dehydration and/or electrolyte imbalance if you try this.

A bit dramatic, considering these are widely food additives to things like gummy bears in similar amounts and stories abound about their effect.

A one time event is unlikely to do too much damage unless you’re already sick.

People should generally not be taking laxatives repeatedly for a prolonged period unless they have a prescribed indication.

> an osmotically balanced solution of polyethylene glycol, typically referred to as Macrogol.

It’s quite common in the US to do plain old miralax and G2 gatorade for outpatient colon prep. There is some controversy about this. But there isn’t much evidence that “osmotically balanced” (the whole concept of osmotic balance is suspect for an osmotic laxative - that works because of its inherent imbalance) has any meaningful benefit other than selling something that sounds good with little evidence.

https://my.clevelandclinic.org/health/articles/21217-miralax...

People that get into trouble are typically abusing laxatives or have chronic kidney, liver or heart disease that put them at risk.


Just get up in the morning and chug a liter of water and then have a cup or two of strong coffee ?


Certain sugar substitutes are laxatives. I had some DELICIOUS sugar free gummy worms from a cracker barrel that gave me the worst shits for a few hours. I only ate like 10-15 of them.


This is the source they used: https://www.giejournal.org/article/S0016-5107(03)01304-X/ful...

Does was 24 grams. For reference, a 12 ounce can of coke has 39 grams of sugar.

However, this was not a double blind study, so mileage my vary.


I’d imagine it works like lactose, and if that’s the case a “regular” dose will do plenty.


Osmotic laxatives such as lactulose need only 10 grams or so for “effect”. Standard dose of say lactulose for cirrhotics is about 20 grams multiple times per day to keep them shitting.




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