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> arbitrarily avoiding stuff which makes you happy is an irrational cognitive bias

I do not generally avoid that - only when it comes to serious decisions. For a pandemic not seen for the last 100 years, I think this precaution is warranted.

Last time I did was when I was receiving conflicting signals - LW was strongly pro crypto, HN strongly against. HN generated warm fuzzy feelings (if crypto succeed it's extreme selfishness, they can't be right because as a community we find it wrong, deflation is good and more generous to newcomers, etc). I waited a bit too long to my taste to get in. A lot of LW people just didn't. It was quite a fiasco - the calculations clearly made sense, but a lot of people didn't act on the advice they were freely given. The reason is still unclear. Personally, I think it's due to these warm fuzzy feelings - or the lack of thereof.

I vowed "never again!", and now I apply a discount factor to questions that appeal to sentiments.

> in experiments where humans were asked to estimate their level of control over the outcome, depressed people were more likely to correctly reason they didn't have [much] control

Good enough for me! In the case of covid, we have little control - if only about the vaccine formula and access. A homemade vaccine allows me more freedom.

I see that as buying an option for a deadly 2nd wave driven by a mutant selected by the evolutionary pressure of everyone being vaccinated against the same antigens.

$1k isn't much for such a deadly scenario: I estimate the odds at 1%, and the lifetime cost at 1M (average cost of a human life), which means the homemade vaccine option is interesting up to $10k.



I suspect a depressed person would be less likely to overestimate their ability to correctly control the strength of a homemade vaccine ;)




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