Of course there is not a shared level regulation among all the states. But generally speaking, the healthcare industry is a highly regulated system, which means higher costs.
It also has something to do with healthcare being an incredibly difficult product to provide requiring extremely smart people to deliver extremely hard to device solutions, which also result in much of the regulation.
Obviously, it’s possible there is too much regulation and resources are not allocated properly, but on its face, I would expect something as complicated and risky as operating on people’s brains and chemotherapy and transplants to be expensive.