Lisp is definitely not going to happen, but given the ongoing expansion of C++ to (to me) unlearnably huge levels I think Rust will find a substantial niche in embedded and HPC systems, not to mention Firefox.
For "just write a thing that works" I've come to really prefer C# for desktop apps and Python for small things.
I have reservations about Rust in HPC. There are simply a lot of libraries missing for scientific computing that you find in Julia, Fortran, Python, Matlab...etc.
You can of course write all your stuff from scratch like several vendors I know have done with C & C++, but I think that is the exception and not the rule.
For "just write a thing that works" I've come to really prefer C# for desktop apps and Python for small things.