I am concerned by the absence of a dose-response until above a threshold concentration for all substances tested. Perhaps osmotic effects, displacement, and chemical competition for receptors, all of which may be in-vitro effects, may explain the curves. Is the threshold relevant to in-vivo concentrations? No idea.
The reason toxicity is expressed as an LD50 is to account for the dose-response of toxins. If toxins behaved as purported in this experiment, we could use a simple concentration number instead: no effect, no effect, no effect, dead.
Also, it looks like all the substances that showed toxic induction did so around the same concentration. Very suspicious for chemically disparate substances with, presumably, different mechanisms of action.
“How can we all have died at the same time? ...(thinks)...The salmon mousse!”
The reason toxicity is expressed as an LD50 is to account for the dose-response of toxins. If toxins behaved as purported in this experiment, we could use a simple concentration number instead: no effect, no effect, no effect, dead.
Also, it looks like all the substances that showed toxic induction did so around the same concentration. Very suspicious for chemically disparate substances with, presumably, different mechanisms of action.
“How can we all have died at the same time? ...(thinks)...The salmon mousse!”