Other software with dongle-based protection has been pirated in the past. There will almost certainly be ways of circumventing this protection if software crackers want to do it.
I can't fathom a reason why "software crackers" don't want to do Cubase and/or Reason though.
The thing is, those "dongle-based protection" have been pirated in the past only in the rare cases where an issue was found in the dongle scheme or keys where leaked, etc. And those don't happen frequently -- whereas any old school copy protection method was broken a few days/weeks at most post release (sometimes even before release, from the demo/alpha versions).
Hasn't happened in 5-10 years for lots of physical key based products, so even if possible again, it's of theoritical and not practical value (we ain't seeing them anytime soon).