Some of the very best reads are one-offs. This comes to mind: http://www.improvresourcecenter.com/mb/tpcs.html
Blogs: Philalawyer.net, 37Signals' Signal Vs. Noise, Blog Maverick, all the Overheard in * blogs
One-offs: 37 Signals' Getting Real, public domain books including Letters to a Stoic and Walden to name a couple
Lifehacker --> http://www.lifehacker.com
NYTimes --> http://www.nytimes.com
Discover Magazine --> http://discovermagazine.com/
Onion --> http://www.onion.com
Valleywag --> http://www.Valleywag.com
http://www.waiterrant.net
http://www.offthebroiler.com (though it really went downhill when the author started trying to eat healthily)
It seems like there used to be more stuff worth reading on the web, but that's probably just my mental facilities going to hell as I get old (x > 30)
http://www.thedailywtf.com/