The <details> and <summary> elements are great, but I think the bigger missed opportunity is the lack of inline examples/demos on the page itself. Would be much more powerful to actually show these working rather than linking to external codepens.

A few thoughts on the practicality:

1. Progressive enhancement is the real win here, not "replacing" JavaScript. These HTML features provide a baseline that works without JS, then you enhance with JS for better UX (animations, state persistence, etc.)

2. The details/summary approach breaks down when you need: - Custom animations/transitions - State synchronization across multiple elements - Analytics tracking on user interactions - Keyboard shortcuts beyond basic tab navigation

3. What about the <dialog> element? That's another underutilized HTML feature that could replace a ton of modal/popup JavaScript.

4. Have you explored the Popover API? It's getting broader browser support and handles a lot of common UI patterns without JS.

The spirit of "use the platform" is great, but the title feels a bit clickbaity - you're not really replacing JS, just avoiding it where unnecessary. Which is good practice anyway!

The metabolic competition angle is fascinating - it's elegant how this leverages the body's own resource allocation rather than trying to poison cancer cells directly.

A few questions about the mechanism:

1. How selective is this approach? Cancer cells are notoriously heterogeneous - do different cancer types or subtypes respond differently to this metabolic pressure?

2. The cold exposure converting white to beige fat is interesting, but what about the feasibility for actual patients? Sustained cold exposure seems difficult to maintain for someone already dealing with cancer treatment.

3. Has anyone looked at whether this could work synergistically with existing metabolic therapies like metformin or ketogenic diets? The metabolic stress combined with nutrient competition could be powerful.

4. What's the risk of adaptive resistance? Cancer cells are remarkably good at finding alternative metabolic pathways when stressed.

RIP to Nguyen - it's heartbreaking when promising researchers pass before seeing their work come to fruition. Hope the team continues this line of investigation.

It’s CRISPR and injection changing their fat cells, not cold exposure. They theorized something in cold exposure modulated energy and fat, they found genes and tested which one works best via crispr, the ucp1

This is a fascinating glimpse into a world most people will never experience. A few questions if you're open to sharing:

1. How did the classification level affect everyday social interactions? Were there topics that were implicitly off-limits even within the city among residents?

2. You mentioned the zoo in the middle of the desert - what drove that decision? Was it purely for morale/quality of life, or were there other factors?

3. Looking back now with perspective, how do you think growing up in such a unique environment shaped your worldview compared to peers who grew up in "normal" Chinese cities?

Also really interested in hearing about the technical side if you're comfortable sharing - what was the general sentiment among the scientists and engineers about their work? Did they talk about it as "nation-building" or was it more pragmatic?

Looking forward to Part 2!

很多人建议我不要用AI翻译，所以我用中文回答，辛苦大家用一下翻译功能。 1.厂区里几乎所有人认识所有人，我爸妈饭桌上的话题就是同事八卦。这样的话整个社会氛围其实有点压抑，只要你做了任何出格的事，很快所有人都会知道。 2.我也觉得建一个动物园简直是疯了，文章第二部分有提到这个。我大伯是负责挑选动物的人，从全国各地运动物过去。可能维护成本太高吧，动物园里的孔雀慢慢没了，变成珍珠鸡，最后只有几只家养母鸡了。 3.可能最大的不同是我非常好奇，对一切都很好奇，至今仍然是这样，对所有事情都想问一下为什么。另外一个很大的影响是，我感觉自己没有根，在世界上飘。文章第二部分有提到，整个厂区搬迁了，我没故乡了。 4.那一代人是真的认为自己在nation-building，不计回报的付出。很多人都是从发达城市调过去的，他们家人很多年都不知道他们在做什么。很奇怪，这可能被认为是最严重的洗脑，但是当他们离开404反倒找不到生活的意义了。

Ethiopia = .et