I believe GUIX is implemented in Scheme which makes Scheme a natural choice for expressing configuration. Lisp tend to be a natural configuration format for anything written in Lisp. Highly functional configuration processing comes practically for free.
I’ve written a personal system in Common Lisp for building third-party software on macOS (coincidentally somewhat similar to GUIX), and I use sandbox-exec to isolate execution so that only intended requisites affect the build process and so that installation is strictly confined to the configured destination directory, no scribbling outside the lines.
I think it’s implied that it’s been zero days since the underlying cause of some such problem turned out to be DNS related. The number zero being hard coded implies that the root of the problem is always DNS. But, let’s give MTU its due.
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